Need To Establish Safety and Effectiveness of Antibiotics Used in Animal Feeds
HRD-77-81: Published: Jun 27, 1977. Publicly Released: Jun 27, 1977.
- Full Report:
The Food and Drug Administration (FDA) has permitted the continued use of low levels of several antibiotics in animal feeds.
The safety and effectiveness of the continued use in animal feeds of several antibiotics, particularly penicillin, tetracyclines, and sulfaquinoxaline, has not been established. The possibility exists that antibiotic-resistant bacteria may develop, and that this resistance may be transferred from animal to man. On April 15, 1977, FDA decided to restrict the use of these drugs in animal feeds. Questions are raised concerning the use of the National Advisory Food and Drug Committee by FDA, including insufficient expertise, conflict of interest, and improper involvement in regulatory matters instead of policy only.
Recommendation for Executive Action
Comments: Please call 202/512-6100 for additional information.
Recommendation: FDA should determine the safety and effectiveness of antibiotics used in animal feeds based on available data, and withdraw approval of any not shown to be safe and effective. Policy advisory committees should be used only to review broad policy questions in accordance with FDA regulations, and their members made aware of their responsibilities with regard to and the restrictions of conflict-of-interest laws and regulations.